| abstract |
A compound of formula (A); wherein ring A is an aromatic ring or a heteroaromatic ring; R 1 is independently halogen, cyano, etc., each of X 1 , X 2 and X 3 is CR 2 or nitrogen, R 2 is independently hydrogen, etc., n is 0, 1, 2, 3 or 4; -D-Y is -O-CH 2 COOH, etc, and G is a substituted amino, a substituted heterocyclic group, etc, or a pharmaceutical acceptable salt thereof, has activities of opening BK channels. |