http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2277048-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_600e21086c882f1de083e0c13936a9f2 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-575 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54306 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
filingDate | 2009-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aea8ec99ca4265db41374527196c9381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_026b335234fda516863b72287e4c7705 |
publicationDate | 2011-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2277048-A1 |
titleOfInvention | A method for sensing a chemical |
abstract | The present invention relates to a method for detecting an analyte (10) in a sample, comprising the steps of: (i) providing a transducer (3) comprising a pyroelectric or piezoelectric element and electrodes which is capable of transducing a change in energy to an electrical signal, and a first reagent (9) immobilised on the transducer, wherein the first reagent has a binding site which is capable of binding to a second reagent (11) in the presence of the analyte or a derivative of the analyte; (ii) introducing the second reagent, the second reagent having a binding site which is capable of binding the first reagent in the presence of the analyte or derivative thereof and having a label (12) attached thereto which is capable of absorbing electromagnetic radiation to generate energy by non-radiative decay, wherein either the first or the second reagent is capable of binding to the analyte or derivative thereof; (iii) exposing the sample to the transducer thereby allowing the analyte or derivative thereof to bind either to the first or to the second reagent; (iv) introducing a masking reagent (13) which is capable of binding to the same first or second reagent as the analyte or derivative thereof, thereby preventing binding of the first reagent to the second reagent; (v) irradiating the sample with electromagnetic radiation; (vi) transducing the energy generated into an electrical signal; and (vii) detecting the electrical signal, wherein steps (ii) to (iv) may occur in any order. |
priorityDate | 2008-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.