Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f62be69efb7ec6c70239f6957e7f834 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-35 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate |
2009-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a61819d8c57a4560ef4281fa11a1c88a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78b067b30525cf9a55265c31d7acdeab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1228429935da23bdf2266c3813bb297e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c34a1ad494add44bd33c51e469338952 |
publicationDate |
2011-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2268662-A2 |
titleOfInvention |
Hypoallergenic hybrid proteins of major group 1 and 2 mite allergens for use in the treatment of allergies |
abstract |
The present invention refers to recombinant ADN molecules coding to hybrids polypeptides of different allergens from D. pteronyssinus useful for the prevention and treatment of allergies, particularly allergies caused by mites. Specifically, the invention describes hybrid proteins composed of fragments of allergens Derp p l y Derp p 2 with hypoallergenic characteristics and maintain their immunogenic capacity, being particularly useful for the treatment of allergy. The invention also describes the production methods of these polypeptides in heterologous expression systems. Besides, the invention describes efficient purification methods of these hybrid proteins. |
priorityDate |
2008-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |