Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8281ac9f4fb11f15a5da018344453338 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0827 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D225-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-00 |
filingDate |
2009-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e8a3f3873f5921eb9f57df16e0757df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c64924fa8beaba18147b6a4638ab89a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b40147b6917e1be028f6ac2767694e8 |
publicationDate |
2011-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2268619-A1 |
titleOfInvention |
Fluorinated macrocyclic compounds as hepatitis c virus inhibitors |
abstract |
The present invention discloses compounds of formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof: ( I ) which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10335409-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10603318-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9296782-B2 |
priorityDate |
2008-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |