http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2265631-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65d20706c15a4bca2a43369448910716 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
filingDate | 2009-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebc5f3d9f89ad888178d059d3c5a093d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7a5ceff2aac6e2bb7874d4ce0e2e1be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aac0bf2294b6cb6004c912d04e0d44ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_724428c819aab227cf18429cf7d3781b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d69346dfbd842e3dc5c795d7804cda41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b1442e24bb467b47bf900e7f28b8835 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45646087cb570a7b68c73a42532a5eb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73d1efe6e7cb96390dfe3b4e4ad2bdfd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1942562cfc179103c10a0f6c6cc6e6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9758408cc59713135b63f66e4efba974 |
publicationDate | 2012-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2265631-B1 |
titleOfInvention | Novel antimicrobial peptides and their application |
abstract | This invention involves four novel peptides of the formulas I, II, III a IV isolated from natural sources and their synthetic analogs of general formula V and VI, where R n 1 represents acyl, alkyl or unprotected amino group, R n 2 represents amid, substituted amid, unprotected carboxylic group or ester, Xaa represents, independently from each other, proteinogenic amino acid, D-amino acid, non-standard amino acid or amino acid with the side chain modification, n means position of the amino acid replacement and m means the number of the replacements in the peptide chain, and their applications as antimicrobial, antiviral, antifungal, antiparasitic and anticancer compounds. Therefore, they are practical for the production of medication for the treatment of microbial, parasitic and fungal diseases and for the cancer treatment. Formulas for summary: H-Gly-Phe-Leu-Ser-Ile-Leu-Lys-Lys-Val-Leu-Pro-Lys-Val-Met-Ala-His-Met-Lys-NH 2 (I) H-VaI-Asn-Trp-Lys-Lys-VaI-Leu-GIy-Lys-IIe-IIe-Lys-VaI-AIa-Lys-NH 2 (II) H-VaI-Asn-Trp-Lys-Lys-IIe-Leu-GIy-Lys-IIe-IIe-Lys-VaI-AIa-Lys-NH 2 (III) H-Val-Asn-Trp-Lys-Lys-Ile-Leu-Gly-Lys-Ile-Ile-Lys-Val-Val-Lys-NH 2 (IV) R 1 -[Xaa n ] m -Gly-Phe-Leu-Ser-Ile-Leu-Lys-Lys-Val-Leu-Pro-Lys-Val-Met-Ala-His-Met-Lys-R 2 (V) R 1 -[Xaa n ] m -Val-Asn-Trp-Lys-Lys-Ile-Leu-Gly-Lys-Ile-Ile-Lys-Val-Val-Lys-R 2 (VI) |
priorityDate | 2008-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.