| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_661b3ea63e73acc96731eb73625b1bc2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf2a3a767ae32dfcda1f4e6642aeadc9 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-554 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
2009-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14ef065e6ae0da4bd638929076b82ebf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d63b5dfc46a8570e4ce4a0021effdd6b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b87d4ce517cd268be74c162afc2a84a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74856c71c8ebf4889dc93a3dbc107968
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a7712f68357f496c010319f7b473f4b |
| publicationDate |
2010-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2265289-A2 |
| titleOfInvention |
Compositions and methods for tissue-specific rnai delivery in vivo |
| abstract |
This invention relates to new formulated lipid particles (FLiPs) comprising at least one of a single or double stranded oligonucleotide, where the oligonucleotide has been conjugated to a lipophile and at least one of an emulsion or liposome to which the conjugated oligonucleotide has been aggregated, admixed or associated. These particles have surprisingly been shown to effectively deliver oligonucleotides to heart, lung and muscle where they effect gene silencing. |
| priorityDate |
2008-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |