http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2260058-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3438811768d5b0caa638b0c8f6c17a92 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-22 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2896 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate | 2009-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9ec02cc215bfe4ca95b6cb6bcc32a9c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a111d8c21e17bbda9880e7c2ea8ed9bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f6a231ea2ce30dfe4fff59c76fdb01b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e6d7e919de30aa3c81f2db2b4067daa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f26c9339643555da240e122abfe243d |
| publicationDate | 2010-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2260058-A2 |
| titleOfInvention | Single variable domains against the notch pathways |
| abstract | The present invention relates to amino acid sequences (also referred to herein as "single variable domain(s) of the invention", "Nanobody™ of the invention" or "Nanobodies™ of the invention ", ilpolypeptide(s) of the invention" ) that are directed against (as defined herein) members of the Notch signalling pathway such as the four mammalian members of the Notch Receptors (Notch-1, Notch-2, Notch-3, Notch-4, hereinafter also "Notch Receptors" ) and the five mammalian members of the Notch Ligands (the Delta-like family with "DLL1", "DLL3", "DLL4" wherein "DLL" stands for Delta-like ligand; the Jagged family with "Jagged-1", "Jagged-2", hereinafter also "Notch Ligands" ), as well as to constructs that comprise or essentially consist of one or more such single variable domain(s) (also referred to herein as "construct of the invention " and "constructs of the invention", "Nanobody™ of the invention " or "Nanobodies™ of the invention",, respectively). In particular, this invention relates to Notch pathway interfering single variable domains down- or up-regulating Notch signaling (also referred to herein as "Notch-antagonists" or "Notch-agonists" ). |
| priorityDate | 2008-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 378.