abstract |
The present invention provides a compound of formula (I): wherein: R 1 is a group selected from -CH 2 OH 1 -NHCOH and R 2 is a hydrogen atom; or R 1 together with R 2 form the group -NHC(O)CH=CH-, wherein the nitrogen atom is bound to the carbon atom in the phenyl ring holding R 1 and the carbon atom is bound to the carbon atom in the phenyl ring holding R 2 , R 3a and R 3b are independently selected from the group consisting of hydrogen atoms and C 1-4 alkyl groups n is an integer selected from O to 6, R 4 is selected from the group consisting of an optionally substituted monocyclic or polycyclic C 3-10 cycloalkyl group, an optionally substituted monocyclic C 5-10 aryl group and, a methyl group which is substituted with one or more substituents selected from C 5-1O aryl and C 5-10 aryloxy groups, wherein the monocyclic or polycyclic C 3-10 cycloalkyl and the monocyclic C 5-10 aryl groups independently are optionally substituted with one or more substituents selected from halogen atoms, C 1-4 alkyl, C 1-4 alkoxy, C 5-10 aryl and C 5-10 aryloxy groups, or a pharmaceutically-acceptable salt or solvate or stereoisomer thereof. |