http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2254412-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05324dcb1cf1d20b8023b975d4cda4ac |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-04 |
filingDate | 2008-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c24cb8cb53c51138dddc3b60dd216560 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15f87411a4f990d9273480d53698540c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_226363f457daaf93cf3c84e15d53a3ae |
publicationDate | 2010-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2254412-A1 |
titleOfInvention | Macrocyclic lactone compounds and methods for their use |
abstract | The present invention provides a pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of the formula (I) wherein R 1 , R 2 , R 3 , R 5 , R 6 , R 8 , M 1 , M 2 , M 3 , M 4 , M 5 , M 6 and M 7 are each independently a member selected from the group consisting of H, C 1-6 alkyl, OH and C 1-6 hydroxyalkyl; R 4 , R 7 and R 9 are each independently selected from the group consisting of C 1-6 alkoxy and OH; R 10 is a member selected from the group consisting of H, -OH, -OP(O)Me 2 , (II), (III), -O-(CH 2 ) n -OH and -O-(CH 2 ) m -O-(CH 2 ) o -CH 3 , wherein subscripts n and m are each independently from 2 to 8 and subscript o is from 1 to 6; each of L 1 and L 4 are independently selected from the group consisting of (IV) and (V) wherein each M 8 is independently a member selected from the group consisting Of C 1-6 alkyl, OH and C1-6 hydroxyalkyl; each of L 2 and L 3 are independently selected from the group consisting of (VI), (VII) and (VIII); and salts, hydrates, isomers, metabolites, N-oxides and prodrugs thereof. |
priorityDate | 2008-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 706.