| abstract |
Novel compositions, formulations and dosage forms comprising stabilized micronized opioid particles are disclosed. Exemplary opioids include oxycodone, oxymorphone, hydrocodone, and hydromorphone, including as free bases or as salts. Stabilized micronized opioid particles having a Dv90 particle size distribution of less and or equal to 10 µ or less than or equal to 20 µ are disclosed. Methods for micronizing an opioid to provide stabilized micronized opioid particles are also disclosed. |