| abstract |
A insulin nasal powder inhalation and its preparing process are provided. The powder inhalation is consist of self-emulsifying freeze-dried powder and pharmaceutically acceptable carriers. The dry powder comprises insulin, fats(s), emulsifier(s), antioxidant(s), supporting agent(s), bio-gel adhesive(s) and pH modifier(s), wherein the emulsifier is a mixture of lecithin and Tween 80, and the amount of fat in the formulation is determined by the surface area and the particle diameter of oil droplet. |