abstract |
Tetrahydrofiiran antibiotics formulated with certain diacylglycerol- poltethyleneglycol (DAG-PEG) lipids have increased water solubility and bioavailabilty. PEG- 12 GDO, PEG- 12 GDLO, PEG- 12 GDM and PEG- 12 GDP are particularly suitable for forming liposomes that incorporate tetrahydrofurans in the bilayer. |