http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2235041-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_74d3a9f0dff3d3664f8f84d5aba0da99 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0817 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-06 |
filingDate | 2008-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cecd0f0fd5b1a478638bbcb2400ddda http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05cb627fdea5cdafb9b409bd6066108e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b47277e49e20cedb42e0c54c8baf4724 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86d980f8f8db13e7da7d1a838f4ed268 |
publicationDate | 2010-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2235041-A2 |
titleOfInvention | Antimicrobial compounds |
abstract | The present invention relates to a compound of formula (I) AA-AA-AA-X-Y-Z wherein, in any order, 2 of said AA (amino acid) moieties are cationic amino acids and 1 of said AA is an amino acid with a lipophilic R group, the R group having 14-27 non-hydrogen atoms; X is a N atom, which may be substituted by a branched or unbranched C 1 -C 10 alkyl or aryl group which group may incorporate up to 2 heteroatoms selected from N, O and S; Y represents a group selected from -R a -R b -, -R a -R b -R b - and -R b -R b -R a - wherein R a is C, O, S or N, and R b is C; each of R a and R b may be substituted by C 1 -C 4 alkyl groups or unsubstituted; and Z is a group comprising 1 to 3 cyclic groups each of 5 or 6 non-hydrogen atoms, 2 or more of the cyclic groups may be fused and one or more of the cyclic groups may be substituted; the Z moiety incorporates a maximum of 15 non-hydrogen atoms; and wherein the bond between Y and Z is a covalent bond between R a or R b of Y and a non-hydrogen atom of one of the cyclic groups of Z. The invention further relates to formulations containing these compounds and their uses in therapy, particularly as antimicrobial or antitumoural agents. |
priorityDate | 2007-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 201.