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filingDate 2008-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b27a613f35cfd9a867b399090808a020
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac63eacd405c6791ee646ef5e02fc04b
publicationDate 2010-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2232265-A1
titleOfInvention Method and kit for quantifying of allergen-especific human igg subclasses for the control and attendance of specific immunotherapy
abstract The present invention provides a method for quantifying the levels of allergen-specific human IgG antibody subclasses, particularly of IgG1, IgG2, IgG3 or IgG4 subclasses, using a reverse ELISA immunoenzymatic technique. The present invention also provides a kit comprising microtitration plates for ELISA already sensitized/covered with monoclonal antibodies, for example, anti-Der p 1 or anti-Der p 2, total extract from corresponding allergens, labeled secondary antibodies, enzymatic conjugate, enzymatic substrate and chromogenic buffer, as well as reference positive and negative control sera. The present invention provides high sensitivity for the detection of specific IgG antibody subclasses and is a potential tool for the control and attendance of allergen-specific immunotherapy in patients with allergic respiratory disease.
priorityDate 2008-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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