abstract |
The present invention relates to a galliated calcium-phosphate biomaterial comprising a gallium-doped phosphocalcic compound of formula (I): n n Ca (10.5-1.5x) Ga x (PO 4 ) 7 (I) n nwherein 0 < x < 1 and the salts, hydrates and mixtures thereof and/or a calcium deficient apatite structure with in particular a (Ca + Ga)/P molar ratio in the range of 1.3 to 1.67, and a gallium content up to 4.5 % by weight. n It also relates to processes of preparation of such materials and uses thereof, in particular as dental or bony implants. n It further relates to a kit comprising a galliated calcium-phosphate biomaterial in combination with a fluid component. n It finally relates to methods of use of the galliated calcium-phosphate biomaterial, notably for III) ions increase radio-opacity after bone implantation and can be released for inhibiting bone resorption. |