http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2226393-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6f677855b41682531902de49afbd5fa |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2009-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d0740b4d7bf768f787f9195a76de859 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d30c97b9d887d722eefeed9cf4fa09c |
| publicationDate | 2010-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2226393-A1 |
| titleOfInvention | CHK2 polymorphism as cancer marker |
| abstract | The invention relates to the use of gene modifications in the human CHK2 ( CHEK2 ) gene coding for checkpointkinase 2, for the prediction of the risk and progression of cancers and for the prediction of the response to pharmacological or non-pharmacological therapies for the treatment of cancers and for prediction adverse drug reactions. Furthermore, the invention relates to the provision of individual gene variants with the aid of which further gene modifications which can be used for the abovementioned purposes can be detected and validated. Such gene alterations may be that the promoter of CHK2 at position -7161 is a guanine to adenine substitution, at position -7235 is a cytosine to guanine substitution, at position -10532 is a guanine to adenine substitution, or at -10621 until -10,649 a deletion of 29 base pairs is present. |
| priorityDate | 2009-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 243.