http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2224962-A2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7317808024e524eea40a6c5a5ad6a22
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1812
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18
filingDate 2008-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c117daa3a89a8d07b6a48f37583937cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30b7d617f815f076abfd6032aebff339
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publicationDate 2010-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2224962-A2
titleOfInvention Non-spherical contrast agents for cest mri based on bulk magnetic susceptibility effect
abstract In magnetic resonance imaging (MRI) based on chemical exchange-dependent saturation transfer (CEST), a novel carrier for CEST contrast agents is provided. The carrier is non-spherical and comprises a semipermeable shell, wherein the shell comprises a paramagnetic compound. The shell encloses a cavitycomprising an MR analyte, wherein the semipermeable shell allows diffusion of the MR analyte. The CEST effect is based on the 5 bulk magnetic susceptibility effect caused by the anisotropy of the carrier. This leads to a versatile carrier that does not require interaction of the analyte with a paramgnetic chemical shift reagent.
priorityDate 2007-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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