| abstract |
The present invention relates to methods for detecting, quantifying and high throughput screening of donor-products and the catalytic activities generating the donor-products in group-transfer reactions. Enzymes catalyzing the group transfer reactions include methyltransferases, sulfotransferases, kinases, glycosyltransferases, uridine glucuronide transferase, UDP- glucuronosyltransferases, acetyl transferases, glutathione transferases, and ADP- ribosyltransferases. The invention further provides immunoassays, antibodies and kits that may be used to practice the methods of the invention. |