Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7f871411f032ed0fb0e077a4ae2816f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2892 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2835 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2008-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_873f57e6e54a3288d75ec9ef3baff186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f8df82dc6354ebe9c409fe986653824 |
publicationDate |
2012-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2214483-B1 |
titleOfInvention |
Methods of identifying histone deacetylase inhibitors useful for neurological disorders |
abstract |
A method of identifying a candidate compound for treatment of a neurological condition includes obtaining a test compound; assaying a first activity of the test compound to inhibit histone deacetylase activity of a histone deacetylase 3 (HDAC3); assaying a second activity of the test compound to inhibit histone deacetylase activity of a histone deacetylase other than a HDAC3; and identifying the test compound as a candidate compound for treatment of a neurological condition if the first activity of the test compound is greater than the second activity of the test compound. |
priorityDate |
2007-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |