| abstract |
A purification method of pemetrexed salts by means of salting-out. The pemetrexed salts are defined as formula (III) in which, (1) If M3+ is H+, then M1+ and M2+ are H+, Li+, Na+ or K+ independently. M1+ and M2+ are the same or not ,but they can not be H+ simultaneously; (2)If M3+ is Li+, Na+ or K+, then M1+ and M2+ are Li+, Na+ or K+ independently. M1+, M2+ and M3+ are the same or not. |