Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f34119b232d292c72e632b62008eca90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1a331d46449cc0bf0e1e9b8bda91158f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-204 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-204 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4168 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4162 |
filingDate |
2009-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ae4acd95bbe3cec395af10d378a0a5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c9cb28119554ca4adb006a468e32560 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f106ccdae95f31fe94d4f353ee271fe8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f127d7c86577d51f9a981f63a19e340a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_902f0511d7776bae977c1d52fc2575f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9474766d240f1399caf4cc1f04c807c |
publicationDate |
2010-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2209466-A2 |
titleOfInvention |
Methods and compositions for treating post-operative pain comprising clonidine |
abstract |
The present invention is directed to an implantable drug depot useful for reducing, preventing or treating post-operative pain in a patient in need of such treatment, the implantable drug depot comprising a therapeutically effective amount of clonidine or pharmaceutically acceptable salt thereof and a polymer; wherein the depot is implantable at a site beneath the skin to reduce, prevent or treat post-operative pain, and the depot is capable of releasing (i) about 5% to about 45% of the clonidine or pharmaceutically acceptable salt thereof relative to a total amount of the clonidine or pharmaceutically acceptable salt thereof loaded in the drug depot over a first period of up to 48 hours and (ii) about 55% to about 95% of the clonidine or pharmaceutically acceptable salt thereof relative to a total amount of the clonidine or pharmaceutically acceptable salt thereof loaded in the drug depot over a subsequent period of at least 3 days. |
priorityDate |
2008-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |