| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f79749e86afce9444a364ab60ca3584
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f6fd8a92f55dca0f111bd7c5858ae83 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-0659
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2018-20355
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B18-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-00084
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2018-2025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2018-20351
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2018-20361
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-067 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-067
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-0616 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-067 |
| filingDate |
2008-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_319a2de3cf2d03f0b8473950a7acea9a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b980bbcfac1b7094d6ed4edb545eaef5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a533ac52c7fc40a8f6182489b296562
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e019600489842862251f3dc0384cc5eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cf0721cf7cc4e62a5e57015f7c8c913 |
| publicationDate |
2010-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2207595-A2 |
| titleOfInvention |
System and method for conditioning animal tissue using laser light |
| abstract |
Systems and methods for prophylactic measures aimed at improving wound repair. In some embodiments, laser-mediated preconditioning would enhance surgical wound healing that was correlated with hsp70 expression. Using a pulsed laser (λ = 1850 nm, Tp =2 ms, 50 Hz, H = 7.64 mJ/cm 2 ) the skin of transgenic mice that contain an hsp70 promoter-driven luciferase were preconditioned 12 hours before surgical incisions were made. Laser protocols were optimized using temperature, blood flow, and hsp70 -mediated bioluminescence measurements as benchmarks. Bioluminescent imaging studies in vivo indicated that an optimized laser protocol increased hsp70 expression by 15-fold. Under these conditions, healed areas from incisions that were laser-preconditioned were two times stronger than those from control wounds. Our data suggest that these methods can provide effective and improved tissue-preconditioning protocols and that mild laser-induced heat shock that correlated with an expression of Hsp70 may be a useful therapeutic intervention prior to or after surgery. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9709551-B2 |
| priorityDate |
2007-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |