http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2205624-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 |
| filingDate | 2008-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c56ac2412e11395f52eba3f7df99f55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1895c77648e17763a70df3f9b279cc9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe159a5cb96d7d04f6d3b9e96c2a05ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6027962d31aa9031998a4d074fef5bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41b4730a7e3edecd06adf733445dde81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f555936a119309d8b385c7c1a1a7385 |
| publicationDate | 2010-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2205624-A1 |
| titleOfInvention | Insulinotropic peptide synthesis using solid and solution phase combination techniques |
| abstract | The present invention relates to the preparation of insulinotropic peptides comprising at least two glutamic acid residues in direct sequence (Glu-Glu) that are synthesized using a solid and solution phase ('hybrid') approach. Generally, the approach includes synthesizing three different peptide intermediate fragments using solid phase chemistry. Solution phase chemistry is then used to add additional amino acid material to one of the fragments. The fragments are then coupled together in the solution phase. The use of a pseudoproline in one of the fragments eases solid phase synthesis of that fragment and also eases subsequent solution phase coupling of this fragment to other fragments. The present invention is very useful for forming insulinotropic peptides such as exenatide(1-39) and its counterparts. |
| priorityDate | 2007-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 403.