http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2203421-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0fc1d89633cf9f0c4322a46c57351f5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-40 |
| filingDate | 2008-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6d3a94631596f0ad73511163484046a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa215942b0284781ea3755293c6f2742 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d62efb1abfa1314a076fca58dbb20d77 |
| publicationDate | 2010-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2203421-A2 |
| titleOfInvention | Methods of synthesis of certain hydroxamic acid compounds |
| abstract | The present invention pertains to the general field of chemical synthesis, and more particularly to methods for the synthesis of certain hydroxamic acid compounds, and in particular, (E)-N-hydroxy-3-(3-phenylsulfamoyl-phenyl)-acrylamide, also known as PXD101 and Belinostat ®, comprising, for example, the steps of: (SAF) sulfonamide formation; (PURC) optional purification; (AAA) alkenyl acid addition, comprising: either (i): the steps of, in order: (ACAEA) alkenyl carboxylic acid ester addition; (PURE) optional purification; and (CAD) carboxylic acid deprotection; or (ii): the step of: (ACAA) alkenyl carboxylic acid addition; (PURF) optional purification; (HAF) hydroxamic acid formation; and (PURG) optional purification. |
| priorityDate | 2007-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 190.