http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2201024-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ece212839c1aa09bbf8c3024a2cce95 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-00 |
| filingDate | 2008-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e8f570f4ab04bff4865025bc8c90404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc9efebd667806a8e599cf7808fe106b |
| publicationDate | 2010-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2201024-A1 |
| titleOfInvention | Peptides inducing a cd4i conformation in hiv gp120 while retaining vacant cd4 binding site |
| abstract | A novel peptides are complexed with HIV-I envelope protein gp120, and causes the protein to assume a CD4i conformation but without occluding the CD4 binding-site of gp120. This peptide-gp120 complex is immunogenic and, upon immunization of subjects, induces broadly-neutralizing antibodies directed to the CD4 binding site of gp120. The peptide preferably consists of a sequence of 8-20 amino acid residues which comprises (a) a core sequence Arg-Xaa1-Asp-Leu-Pro-Xaa2-Trp-Ala (SEQ ID NO: 1) in which Xaa1 and Xaa2 is any amino acid, or (b) certain substitution variants of SEQ ID NO:1. |
| priorityDate | 2007-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 680.