http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2198294-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-9406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4064 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
| filingDate | 2008-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d915738a6cc5e6b5ec425b8a368affa2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1241893609003b40a3fbaa571ca9bf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dee6dc8bf17e09fca1082edc5707c23 |
| publicationDate | 2010-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2198294-A2 |
| titleOfInvention | Method for measuring neurotransmitters in vivo |
| abstract | The invention relates to a method for the in vivo detection of a biochemical substance in an animal by culturing neurofluocytes which stably express a receptor for biochemical substances by transfection of cells with cDNA of the receptor and a marker that will emit a detectable energy in the presence of the biochemical substance, implantation of the neurofluocyte in the brain of the animal; and detecting the energy emission of the marker. In a first embodiment, the biochemical substance is a neurotransmitter, the label is a phosphor, and the detection step includes forming an opening in the skull of the animal and the optical detection of fluorescent using a two-photon laser scanning microscope. Multiple biochemicals can be simultaneously detected by culturing neurofluocytes that express different receptors and having different phosphor labels that produce fluorescent signals at distinguishable wavelengths. |
| priorityDate | 2007-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 212.