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publicationDate 2010-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2191893-A1
titleOfInvention Analysis method and devices for biological reactions between a liquid and a solid phase
abstract The invention relates to an apparatus for performing immunological, histological and cytochemical, molecular biological, enzymological, clinical chemical and other analyzes, comprising a slide with one or more elongate adhesive surfaces and a reagent carrier with one or more grooves. The slide may be releasably connected to the reagent carrier such that the elongate adhesion surfaces are respectively opposite one of the grooves and, when reactants bound to a solid phase are disposed on the elongated adhesion surfaces and reactants dissolved in liquid are in the grooves, the reactants and reactants are in contact. Means are provided to prevent the passage of liquid from a gutter into an adjacent gutter. A method for carrying out a corresponding analysis can be carried out with this device by connecting the slide to the reagent carrier so that the elongate adhesion surfaces are each opposite a groove, liquid with dissolved reactants is introduced into the grooves, so that the adhesive surface is arranged on the adhesion surface Stepping substrates with the reaction partners bound thereto come in contact with the liquid, and slides and reagent carriers are moved together so that the liquid moves alternately in the two longitudinal directions of the grooves.
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