http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2185523-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-498 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-88 |
| filingDate | 2008-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1398d062a9a6850b30d729154aeb4d64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c24938667307fc0cb9d3a22f851935a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e769ebac9c6343b7315103daf3974f42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5d259c24d6b688a5ab0c25b87ce8a44 |
| publicationDate | 2010-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2185523-A2 |
| titleOfInvention | Derivatives of 1-oxo-1,2-dihydroisoquinoline-5-carboxamides and of 4-oxo-3,4-dihydroquinazoline-8-carboxamides, preparation thereof and application thereof in therapeutics |
| abstract | The invention relates to the derivatives of 1-oxo-1,2-dihydro-isoquinoline-5-carboxamides and of 4-oxo-3,4-dihydroquinazoline-8-carboxamides, of general formula (I) in which: R1 represents a hydrogen atom, a (C1-C10)alkyl, (C3-C7)cycloalkyl, (CH2)n-(C1-C6)alkenyl, (CH2)n-(C1-C6)alkynyl or (C1-C6)alkyl-Z-(C1-C6)alkyl group in which Z represents a heteroatom chosen from O, N and S(O)m, or else R1 represents a COOR or S(O)mR group, an aryl or an aralkyl, the (C1-C10)alkyl, (C3-C7)cycloalkyl, (CH2)n-(C1-C6)alkenyl, (CH2)n-(C1-C6)alkynyl, (C1-C6)alkyl-Z-(C1-C6)alkyl, aryl or aralkyl groups; R2 represents one or more groups chosen from a hydrogen atom, a halogen atom, a (C1-C6)alkyl, (C3-C7)cycloalkyl, (C1-C6)alkenyl, (C1-C6)alkynyl or (C1-C6)alkyl-Z-(C1-C6)alkyl group, in which Z represents a heteroatom chosen from O, N and S(O)m, or else R2 represents a halo(C1-C6)alkyl, halo(C1-C6)alkoxy, hydroxy, (C1-C6)alkoxy, nitro, cyano or amino group, an NR7R8, COOR, CONR7R8, OCO(C1-C6)alkyl or S(O)m-NR7R8 group, or an aryl group; R4 and R5 represent, independently of one another, a hydrogen atom, or else R4 and R5 form, with the carbon atom which bears them, a saturated ring containing from 3 to 6 carbon atoms and optionally containing from 0 to 1 heteroatoms chosen from O, N or S; R6 represents a group chosen from a hydrogen atom, a halogen atom, a (C1-C6)alkyl, (C3-C7)cycloalkyl or (C3-C7)cycloalkyl(C1-C6)alkyl group, a halo(C1-C6)alkyl, nitro or amino group, an NR7R8 or COOR group, an NR7(SO2)R8 or CONR7R8 group, or an aryl group; X represents a carbon atom or a nitrogen atom; m represents an integer between 0 and 2 and n represents an integer between 1 and 6. Method of preparation and application in therapeutics. |
| priorityDate | 2007-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.