http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2173892-B8
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdf7b8916345b671dbfd9676e6b00021 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P37-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P37-04 |
| filingDate | 2007-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4ee269e479fdcff3b470436c5c813ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8701d56b029bfacb9c773ded7d5b21d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad34658b1138d35d787d90ed3cda269b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c2e25d1db6e00bc29a7a3dd09552baf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b37f3380501c807dd13a1030c8041f33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a656e938af3074f07f35a105e4d7fa74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed567c613b36f4bb61adfd2b1ed2b0db |
| publicationDate | 2012-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2173892-B8 |
| titleOfInvention | Process for the preparation of immobilised recombinant Penicillin Acylase biocatalyst from Achromobacter sp CCM 4824 expressed in E. coli BL21 CCM 7394 and its use for the synthesis of beta-lactam antiobiotics |
| abstract | The present invention discloses isolation of Penicillin Acylase (PA) from Achromobacter sp CCM 4824 expressed in recombinant strain E. coli BL21 CCM 7394 bearing the recombinant plasmid pKXIPl and processing of PA into biocatalyst useful for the industrial synthesis of antibiotics. More particularly the invention discloses a synthesis of semi-synthetic β-lactam antibiotics in the reaction mixture consisting of activated acyl- donor (D-p-hydroxyphenylglycine methyl ester or amide for Amoxicillin and Cefadroxil; D-phenylglycine methyl ester or amide for Ampicillin and Cephalexin) and nucleophile (6-APA or 7-ADCA) catalyzed by PA obtained from recombinant E.coli BL21 CCM 7394 as the biocatalyst. |
| priorityDate | 2007-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 187.