| abstract |
The invention provides cytokine modulators and methods for using them to modulate cytokine production in derived monocyte-derived cells. In particular, the cytokine modulators of the invention selectively bind to a T cell cytokine inducing surface molecule (TCISM) - a T lymphocyte ligand or the corresponding TCISM - the derived monocyte lineage cell receptor, thereby modulating cytokine production in derived monocyte-derived cells. |