http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2173767-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12030ffbc539df5b155e08d951f57a7c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-475 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475 |
filingDate | 2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e352126f88d62dbea7491f812ea0119 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43194206f3222e557e44205baaa48a28 |
publicationDate | 2010-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2173767-A1 |
titleOfInvention | Optimized purification process of recombinant growth factor protein |
abstract | A process for the production of a purified recombinant GDF-5 related protein in prokaryotes comprises the steps of bacterial cell disruption and inclusion body solubilization to obtain a solubilized monomer of a GDF-5 related protein, said process characterized by a) disruption of bacterial cells with a high pressure homogenizer at a disruption pressure between 800 and 900 bar; and/or b) treatment of the recovered inclusion bodies with a denaturing solubilization buffer comprising L-arginine. |
priorityDate | 2007-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.