http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2173718-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fece74aa8c0cb73d997c194165159cc |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
filingDate | 2008-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0d2a9a5af53ed5661f06f523c200cdb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da965a0cce529b1e83f2e14fa05aae90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bff459d7e7d221e33194a0798ff64f70 |
publicationDate | 2010-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2173718-A2 |
titleOfInvention | A method for isolation and purification of montelukast |
abstract | A method of isolation of Montelukast of formula I from reaction mixtures, comprising conversion of the crude substance to well-crystallizing salts with primary amines in the environment of at least one organic solvent and acetonitrile, followed by re-crystallization of these salts with simultaneous removal of chemical impurities and use of the chemically pure salts of Montelukast with primary amines for direct transformation to the pharmaceutically useful amorphous form of Montelukast sodium of formula II. |
priorityDate | 2007-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.