| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59e1d955a7b1560dc68cf7fd800e8fac |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-732 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-303
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6408
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
| filingDate |
2008-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32b8be36a5698e3f0426607dd880b091
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f19c561a6425bf1e137cd351d3459fc1 |
| publicationDate |
2010-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2169404-A1 |
| titleOfInvention |
Method for measuring bonding activity of antibody which mimics antibody-dependent cell-mediated cytotoxic activity |
| abstract |
The present invention provides a simple method which is capable of evaluating the binding activities of an antibody to both an antigen and an Fc receptor. n Disclosed is a method of measuring the binding activities of an antibody to both an antigen or antigen epitope and an Fc receptor or a fragment thereof, comprising a step of mixing the antibody with the antigen or antigen epitope labeled with one member of a set of donor and acceptor capable of fluorescent resonance energy transfer and the Fc receptor or fragment thereof labeled with the other member of the set of donor and acceptor; a step of irradiating the resultant mixture with light having a wavelength capable of exciting the donor; and a step of measuring the fluorescence level of the mixture. Also provided are a method of estimating the ADCC activity of an antibody, a method of controlling the quality of an antibody, a method of manufacturing an antibody, a method of screening for antibodies, and kits for use in these methods. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013140074-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3341738-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9409994-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9880176-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2988174-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2980271-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013038113-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013181543-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10900965-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103959063-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103959063-B |
| priorityDate |
2007-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |