http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2167506-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b9d212083c297d5c75d3b97ac90a50f |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-08 |
filingDate | 2008-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_593634a1e8f45c35b101d3d10a63e0cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12d15bb2c78c07cf67ffbce1684f73f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_026cb1b2647e5182e2ba8885735729dc |
publicationDate | 2010-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2167506-A2 |
titleOfInvention | Method for producing n-methylnaltrexone bromide |
abstract | The invention relates to a method for producing n-methylnaltrexone bromide, a compound of the general formula (I), X' meaning an anion that is different from bromide anion, and R meaning hydrogen or a leaving group, being dissolved or dispersed in a suitable polar solvent, said solution or dispersion being mixed with a compound containing bromide anions, and the resulting reaction mixture being stirred until the n-methylnaltrexone bromide is formed and crystallized, wherein, in the case that R means a leaving group, said group is removed during or after the reaction. |
priorityDate | 2007-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.