http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2164986-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_694f81756e92c09f407b691917f41467 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44f04d319aaa6e66f240244bc905f452 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01Q60-42 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
filingDate | 2008-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffc4eaf28c35afcdbf53e588bc2fe46b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d68f37207b03813c469f1cd8e9f7526 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a78b86751ecd16640d92e243a1ef925 |
publicationDate | 2010-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2164986-A2 |
titleOfInvention | Atomic force microscope as an analyzing tool for biochip |
abstract | The present application discloses a method for detecting a presence of target ligand in a fluid medium which includes the steps of: (i) contacting the fluid medium with a solid substrate that includes an array of dendrons on its surface, wherein each of the dendron includes a central atom, a probe that is attached to the central atom optionally through a linker, and a base portion attached to the central atom and having a plurality of termini that are attached to the surface of the solid support; and (ii) determining the presence of a probe-target ligand complex by measuring binding force between the bound ligand and detection molecule tethered to the tip of an atomic force microscope ('AFM'), which detection molecule has affinity for the ligand, wherein measurement of an increase in force between the probe-target ligand complex and the detection molecule by AFM indicates the presence of the probe-target ligand complex. |
priorityDate | 2007-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 487.