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filingDate 2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2010-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2162539-A2
titleOfInvention Minor splicosome assay system for modulating cell division
abstract Assay system for the inhibitory or activating modulation of the cell division in eukaryotes comprising at least one cellular in-vivo system comprising at least one spliceable pre-mRNA which comprises at least one intron and whose splicing is dependent on at least one snRNA U12 or U11 or U6atac or U5 or U4atac and the pre-mRNA comprises, in (a), at least one splicing site for U12 or U11, in the presence of at least one substance of interest, and a detectable signal is induced, if appropriate together with further auxiliaries.
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