| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_015c27707dd641eb59768a705b23690b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate |
2009-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee85b08b1523042ae15e0c9f10dcfacb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca0c55358dd4093594f096a307037acc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39d1926949ff15603bafa71df38656f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f47df6f1b2691b5f1ebe3555b12df2bc |
| publicationDate |
2011-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2151442-A3 |
| titleOfInvention |
Process for preparing temozolomide |
| abstract |
Described is a new process for producing temozolomide, comprising the reaction between 5-aminoimidazole-4-carboxamide and N-succinimidyl-N'-methyl carbamate and the subsequent reaction of the thus obtained carbamoyl 5-aminoimidazole-4-carboxamide with sodium nitrite. Temozolomide is then purified by chromatography on adsorbent polymeric resin and subsequent crystallization from water and acetone. |
| priorityDate |
2008-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |