http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2136803-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4196 |
filingDate | 2008-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8629f9a3f90719ed6461af49537fb17b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8a54626aa919f8f8fc3a26f069a3a50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa96bfedc2342c91c834b615209f2794 |
publicationDate | 2012-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2136803-B1 |
titleOfInvention | Triazole derivatives which are smo antagonists |
abstract | The present invention provides a method for the treatment or prevention of conditions which can be ameliorated by Smo antagonism, which method comprises administration to a patient in need thereof of an effective amount of a compound of formula I or a composition comprising a compound of formula I: or a pharmaceutically acceptable salt or solvate thereof; wherein: 2 of X, Y and Z represent nitrogen atoms, and the other represents an oxygen atom; R1 and R2 are taken together with the atom to which they are attached and represent a cyclobutyl ring, optionally substituted with 1-2 fluorine atoms, and R3 represents hydrogen or a fluorine atom; or R1 represents methyl, R2 represents methyl or a fluorine atom and R3 represents a fluorine atom. |
priorityDate | 2007-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 711.