http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2135870-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 |
| filingDate | 2008-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_021bf9e4fb6f327fd320976eb0b139c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d9cb29d77c9d38ea34786b213402555 |
| publicationDate | 2012-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2135870-B1 |
| titleOfInvention | Process for production of mirtazapine |
| abstract | The invention provides a process for the production of mirtazapine by which high-purity mirtazapine which is safely usable as drug can be simply and easily obtained from a reaction fluid obtained by ring-closing reaction of 2-(4-methyl-2 -phenylpiperazin-1-yl)pyridine-3-methanol with concentrated sulfuric acid. A process for the production of mirtazapine, characterized by subjecting a reaction fluid obtained by ring-closing reaction of 2-(4-methyl-2-phenylpiperazin -1-yl)pyridine-3-methanol with concentrated sulfuric acid to dilution with water, alkalizing the obtained dilution in the presence of propanol to extract mirtazapine into the propanol, and crystallizing mirtazapine from the resulting extract. |
| priorityDate | 2007-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.