http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2134438-A1

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filingDate 2008-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f43f163f8f48bddba4c80a4f6c8eefb9
publicationDate 2009-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2134438-A1
titleOfInvention Apparatus and method for filter cleaning by ultrasound, backwashing and filter movement during the filtration of biological samples
abstract The present application is directed to the separation of- a solid fraction from a fluid sample particularly a therapeutic cellular fraction from a biological sample such as a bone marrow sample by a porous filter (2) which separates a filtration unit (1) into an upper pre-filtration chamber (3) into which a fluid sample (4) requiring cell separation is introduced and a lower post-filtration chamber (5) into which a fluid (6) capable of transmitting an acoustic standing wave is introduced. An acoustic element (8) is coupled to a substrate (7) which is located within and at the bottom of the lower chamber (5) and which resonates in response to the acoustic generating element (8) and generates a standing wave through the two fluid phases and the filter to agitate the sample (4). Simultaneously, a cyclic process of vacuum draw (9). causes movement of the sample (4) downwards through the filter (2). Vacuum pressure, fluid flow rate and frequency of vibration are controlled from a remote unit housing appropriate pumps and valves.
priorityDate 2007-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 28.