http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2121973-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b2c547246eb50122150f985e9b1c8a0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20 |
| filingDate | 2008-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68fbe918800452296cfce082c33a119b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3483f04a6c35d6d797939e047d819071 |
| publicationDate | 2009-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2121973-A1 |
| titleOfInvention | Method for discriminating single nucleotide polymorphisms (snps) |
| abstract | The present invention provides a method for discriminating single nucleotide polymorphisms (SNPs) which offers improved sensitivity and specificity. The invention relates also to a test kit. Thus, the present invention is a method for genotyping in typing assays applied to a biological sample, the sample containing one nucleic acid target of interest, the target nucleic acid being susceptible to contain a single nucleotide polymorphism (SNP), comprising the steps of: performing a real-time amplification of the target, generating multiple copies of amplicons, in presence of at least two different labeled probes, each probe allowing real-time detection at the SNP position of both the wildtype and at least one possible mutation, - assessing the discriminatory variable value(s) based on the signals of each combination of two detection probes, and - discriminating between the genotypes. The present invention is especially useful in methods for diagnostic, preventive and therapeutic applications. |
| priorityDate | 2007-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.