Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6a5733ba8a6dc39ffacfd824bbb5ca1e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
filingDate |
2008-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_195d089a316536fa31729f2e4cc1eb81 |
publicationDate |
2009-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2120899-A1 |
titleOfInvention |
Antihypertensive drug combination |
abstract |
Therapeutic combinations and pharmaceutical compositions are provided comprising darusentan and an inhibitor of renin activity or release in absolute and relative amounts effective to provide a beneficial change in a subject's 24-hour pattern of systolic and/or diastolic blood pressure. There are further provided methods of using such combinations or compositions to treat hypertensive disorders, or to lower blood pressure in subjects exhibiting resistance to a baseline antihypertensive therapy. |
priorityDate |
2007-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |