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publicationDate 2009-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2120881-A2
titleOfInvention Method of determining the weight of the coating to be applied to form a controlled release dosage form
abstract A method of coating spherical particles of a beta blocker compound which is based on (a) determining the surface area of a weighed sample of said spherical particles; (b) determining the weight of coating material per surface area unit of spherical particles that will provide a desired release profile for said beta-blocker; (c) determining the surface area of a subsequent batch of spherical particles containing the same beta; (d) coating the subsequent batch of spherical particles with the coating applied in step (b) to provide a coating having substantially the same weight of coating material per surface area unit of spherical particles as determined in step (b).
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