| abstract |
The present invention relates to drugs consisting of unsaturated fatty amino-acid derivatives of the general formula (I), and to their pharmaceutically acceptable acid addition salts, in which: X is oxygen or NH, Rn are independently hydrogen or a (C 1-C 6)alkyl optionally substituted by halogen; R 1 is hydrogen, fluorine, chlorine or bromine, or a CF3 or CHF2 or a (C 1-C 6)alkyl, (C 1-C 6)alkenyl or (C 1-C 6)alkynyl, optionally substituted by one or more halogen atoms; R is hydrogen or a (C 1-C 6)alkyl or (C 3-C 6)cycloalkyl optionally substituted by one or more halogen atoms; Ra and Rb are independently hydrogen (C 1-C 6)alkyl or (C 1-C 6)acyl, and Ra and Rb a hydrocarbonated cycle containing 4 to 6 carbon atoms; and n is an integer between 2 and 14. |