http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2097743-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbffa3b81b3b862dc7220b5648f5f745 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
| filingDate | 2007-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d91740b20224b5f09dd8fbf39d70746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ead6fc14eb47d94aa3443596b1b7056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2069a031604d7244ee919ffd2b1b3346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ae82a1834b7c40a3e720a544e3c8bde http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_332201f147bba1c58e6a6ef5b3141c43 |
| publicationDate | 2009-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2097743-A1 |
| titleOfInvention | Method for screening essential metabolites in growth of microorganisms |
| abstract | The present invention disclosed is a method for screening metabolites essential for the growth of microorganism using metabolic flux analysis. More specifically, the present invention relates to the method for screening metabolites essential for the growth of microorganism, by selecting a target microorganism, constructing a metabolic network model of the selected microorganism, inactivating the consumption reaction of each of metabolites in the constructed metabolic network model, analyzing the metabolic flux of the metabolites to select metabolites essential for the growth of the microorganism, and confirming the selected metabolites using the utilization of each of the metabolites, defined as flux sum (Φ ). According to the present invention, metabolites essential for the growth of microorganism, and genes involved in the essential metabolites, can be screened in a convenient manner, and drug-target genes against pathogenic microorganisms can be predicted by deleting genes associated with the metabolites screened according to the method. |
| priorityDate | 2006-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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