| abstract |
The present invention relates generally to the field of inhibitors of stearoyl-CoA desaturase, such as heterocyclic derivatives, and uses for such compounds in treating and/or preventing various human diseases, including ihose mediated by stearoyl-CoA desaturase (SCD) enzymes, preferably SCDl, especially diseases related to elevated lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome, dermatological disorders and the like. The invention provides compounds of formula (I): X is N or CH; Y is NH, O, S or N-CH3; Q is formulae (a), (b), ou (c). |