| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_459549086df37b5bed0003502de7e7aa |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D411-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D327-00 |
| filingDate |
2007-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f866991db10f7611d2552774158bc875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e6033f3d2606c2ebe54ad15e24329f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59d501a9b8a2a606d47b3daeb64a6e36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80c57a23abc85c0513d3fa9cbdf3a3c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f97cb103c1be2c255dec96977883293
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff5429af211fcd0c14dc545b11a430bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f313432d510e909e063a4abc06d0731e |
| publicationDate |
2009-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2086955-A2 |
| titleOfInvention |
An improved process for the manufacture of cis(-)-lamivudine |
| abstract |
An improved process for the manufacture of Lamivudine. The process involves: (a) resolution of racemic lamivudine (intermediate of formula IX) to cis (±) lamivudine of formula (XII) by forming a crystalline salt and separating the product from an organic solvent by fractional crystallization; (b) resolution of cis (±) lamivudine to cis (-) isomer involving formation of S-binol adduct of formula (XIV). |
| priorityDate |
2006-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |