Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01c1c772cb413705d2e5ce86e337e46c |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y205-01006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1085 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 |
filingDate |
2007-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bd1e2e64c4524becd06ca1a59323984 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_447189f06d03d00f722ebea9e6797900 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b97f21c59ad96f096b1b75385c0bb3f9 |
publicationDate |
2009-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2071022-A1 |
titleOfInvention |
S-adenosylmethionine synthetase mutants, the dnas encoding the same and uses of the mutants |
abstract |
The invention discloses a series of Methanococcus jannaschii S-adenosylmethionine synthetase mutants with improved thermostability and high catalytic activity obtained by using gene mutation technique, characterized in that these mutants refer to an enzyme using Sequence 2 in the Sequence Listing as the reference sequence and contains at least one mutation at position 102, position 93, position 230, and position 357 and has a catalytic activity at least 70% higher than that of the wild-type S-adenosylmethionine synthetase using adenosine triphosphate (ATP) and methionine as substrates. These S-adenosylmethionine synthetase mutants can be used in the production of S-adenosylmethionine. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9803180-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116355875-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016534719-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235084-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2871234-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116355875-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015067331-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235084-A |
priorityDate |
2006-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |