| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
| filingDate |
2007-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87cd5868efcf23fdec200fd986240205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63ebe969e1e082495187709dbee474a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e92286f4b3483c74eda52746ab43239e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_773b9e1bdbb96a593e13a24abfcd18cd |
| publicationDate |
2009-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2069500-A2 |
| titleOfInvention |
Compositions comprising a sirna and lipidic 4,5-disubstituted 2-deoxystreptamine ring aminoglycoside derivatives and uses thereof |
| abstract |
The present invention relates to a composition comprising a siRNA and a transfecting compound consisting of an aminoglycoside of the class of 4,5-disubstituted 2-deoxystreptamine ring linked via a spacer molecule to a lipid moiety of formula - (R1)R2 wherein R1 and R2 represent, independently of one another, a hydrogen atom or a fatty aliphatic chain or R1 or R2 is absent, with the proviso that at least one of R1 and R2 represents a fatty aliphatic chain; or -OR3 or -NR3 wherein R3 represents a steroidal derivative. The invention also concerns in vitro and in vivo applications of these compositions. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2018359904-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019090359-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111386105-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111386105-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021502346-A |
| priorityDate |
2006-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |