http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2065474-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efd09c296645384c4e1c770411f7aa01 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2007-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fd2e3b4b8ec269eadfe50b89987db70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b87c752484b0c815af59885638d0aa0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82154666d207d8161761b9020848c33c |
| publicationDate | 2009-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2065474-A1 |
| titleOfInvention | A method to assess prognosis and to predict therapeutic response to endocrine treatment |
| abstract | The present invention is related to a method for predicting a clinical response of a patient suffering from or at risk of developing a neoplastic disease to a given mode of treatment by determination the status of at least one hormone receptor selected from the group comprising estrogen receptor, progesterone receptor and/or androgen receptor, said method comprising the steps of: na) obtaining a biological sample from said patient; nb) determining the status of at least one hormone receptor selected from the group comprising estrogen receptor, progesterone receptor and/or androgen receptor in said sample, using at least two determinations selected from the group comprising: naa) determining the expression level of the RNA transcripts of at least one gene encoding for a hormone receptor selected from the group comprising estrogen receptor, progesterone receptor and/or androgen receptor, and/or nbb) determining the DNA amplification level of at least one gene encoding for a hormone receptor selected from the group comprising estrogen receptor, progesterone receptor and/or androgen receptor, and/or ncc) determining the presence or absence of at least one single nucleotide polymorphism of at least one gene encoding for a hormone receptor selected from the group comprising estrogen receptor, progesterone receptor and/or androgen receptor; n nc) comparing the pattern of expression level(s) of aa), amplification level(s) of bb) and/or the single nucleotide polymorphism(s) of cc) determined in step b) with one or several reference pattern(s) of expression and/or amplification levels and/or single nucleotide polymorphisms; and nd) predicting therapeutic outcome for said given mode of treatment in said patient from the outcome of the comparison in step c). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10175240-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11221334-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023099350-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-029563-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014031164-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104685072-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9617602-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3653733-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014018926-A1 |
| priorityDate | 2007-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 697.